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hb14  (Miltenyi Biotec)


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    Structured Review

    Miltenyi Biotec hb14
    Hb14, supplied by Miltenyi Biotec, used in various techniques. Bioz Stars score: 97/100, based on 183 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/hb14/product/Miltenyi Biotec
    Average 97 stars, based on 183 article reviews
    hb14 - by Bioz Stars, 2026-02
    97/100 stars

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    A. Cell surface staining of <t>CD40</t> protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. B. Quantification of cell surface staining of CD40 protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. C. Western blots of CD40 in H23, PC-3, H1666, and H1648 NSCLC cells after shRNA-mediated KD. D. Proliferation of H23, PC-3, H1666, and H1648 NSCLC cells following CD40 KD. PrestoBlue was used for cell proliferation measurements every day till 6 days post seeding. P value was determined by Friedman test. E. Bar graph showing growth of H23 xenograft tumor in Athymic nude mice. F. Bar graph showing growth of H23 xenograft in NGS mice G. Bar graph showing weight of tumors at endpoint in corresponding groups. P value was determined by two tailed paired t-test. H. Representative images of excised tumors from indicated groups.
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    MedChemExpress cd40 specific inhibitor traf stop
    A. Cell surface staining of <t>CD40</t> protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. B. Quantification of cell surface staining of CD40 protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. C. Western blots of CD40 in H23, PC-3, H1666, and H1648 NSCLC cells after shRNA-mediated KD. D. Proliferation of H23, PC-3, H1666, and H1648 NSCLC cells following CD40 KD. PrestoBlue was used for cell proliferation measurements every day till 6 days post seeding. P value was determined by Friedman test. E. Bar graph showing growth of H23 xenograft tumor in Athymic nude mice. F. Bar graph showing growth of H23 xenograft in NGS mice G. Bar graph showing weight of tumors at endpoint in corresponding groups. P value was determined by two tailed paired t-test. H. Representative images of excised tumors from indicated groups.
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    Image Search Results


    A. Cell surface staining of CD40 protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. B. Quantification of cell surface staining of CD40 protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. C. Western blots of CD40 in H23, PC-3, H1666, and H1648 NSCLC cells after shRNA-mediated KD. D. Proliferation of H23, PC-3, H1666, and H1648 NSCLC cells following CD40 KD. PrestoBlue was used for cell proliferation measurements every day till 6 days post seeding. P value was determined by Friedman test. E. Bar graph showing growth of H23 xenograft tumor in Athymic nude mice. F. Bar graph showing growth of H23 xenograft in NGS mice G. Bar graph showing weight of tumors at endpoint in corresponding groups. P value was determined by two tailed paired t-test. H. Representative images of excised tumors from indicated groups.

    Journal: Cancer letters

    Article Title: CD40 Drives Tumor Growth in Non-Small Cell Lung Cancer via non-canonical Immune-Independent Mechanisms

    doi: 10.1016/j.canlet.2025.218151

    Figure Lengend Snippet: A. Cell surface staining of CD40 protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. B. Quantification of cell surface staining of CD40 protein in H23, PC-3, H1666, and H1648 NSCLC cells, after shRNA-mediated KD. C. Western blots of CD40 in H23, PC-3, H1666, and H1648 NSCLC cells after shRNA-mediated KD. D. Proliferation of H23, PC-3, H1666, and H1648 NSCLC cells following CD40 KD. PrestoBlue was used for cell proliferation measurements every day till 6 days post seeding. P value was determined by Friedman test. E. Bar graph showing growth of H23 xenograft tumor in Athymic nude mice. F. Bar graph showing growth of H23 xenograft in NGS mice G. Bar graph showing weight of tumors at endpoint in corresponding groups. P value was determined by two tailed paired t-test. H. Representative images of excised tumors from indicated groups.

    Article Snippet: CD40 inhibitor DRI- C21045 (MedChemExpress) and CD40-TRAF6 inhibitor (Sigma, SML1160) were used as indicated.

    Techniques: Knockdown, Staining, shRNA, Western Blot, Two Tailed Test

    A. Representative Flowcytometry dot plot showing BrdU staining in H23 cells following CD40 KD. B. Bar graph showing the relative BrdU population in indicated group. P value was determined using one way ANOVA. C. Representative DNA fiber tracks in indicated groups. D. Dot plot depicting the length of CIdU track in indicated group. P value was determined using one way ANOVA. E. Alkaline comet assay showing ssDNA damage in indicated cell following CD40 KD. dot plot showing change in comet tail length. P value was determined using two-tailed t-test. F. Western blot showing expression of indicated proteins in p53 proficient H23 and p53 mutant H1648 cells following CD40 KD.

    Journal: Cancer letters

    Article Title: CD40 Drives Tumor Growth in Non-Small Cell Lung Cancer via non-canonical Immune-Independent Mechanisms

    doi: 10.1016/j.canlet.2025.218151

    Figure Lengend Snippet: A. Representative Flowcytometry dot plot showing BrdU staining in H23 cells following CD40 KD. B. Bar graph showing the relative BrdU population in indicated group. P value was determined using one way ANOVA. C. Representative DNA fiber tracks in indicated groups. D. Dot plot depicting the length of CIdU track in indicated group. P value was determined using one way ANOVA. E. Alkaline comet assay showing ssDNA damage in indicated cell following CD40 KD. dot plot showing change in comet tail length. P value was determined using two-tailed t-test. F. Western blot showing expression of indicated proteins in p53 proficient H23 and p53 mutant H1648 cells following CD40 KD.

    Article Snippet: CD40 inhibitor DRI- C21045 (MedChemExpress) and CD40-TRAF6 inhibitor (Sigma, SML1160) were used as indicated.

    Techniques: BrdU Staining, Alkaline Single Cell Gel Electrophoresis, Two Tailed Test, Western Blot, Expressing, Mutagenesis